Slike: Antidepressant Like Effect Of Icariin And Its Possible Mechanism In Mice

Antidepressant Like Effect Of Icariin And Its Possible Mechanism In Mice

Effect of garlic extract on immobility periods in tst and fst. Icariin was found to significantly shorten immobility time in the forced swimming test fst after orally administration for 21 consecutive.

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Antidepressant And Anxiolytic Effects Of Garcinia Indica

Antidepressant like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress.

Antidepressant like effect of icariin and its possible mechanism in mice. Antidepressant like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress author links open overlay panel jing sun a 1 fangyan wang b 1 guangliang hong c 1 mengqi pang d hailing xu d haixiao li d feng tian d renchi fang d ye yao d jiaming liu d. Mk801 and 2 amino 7 phosphonopentanoic acid ap7 two nmda antagonists administered to mice all mimicked the effect of clinically effective antidepressants in the forced swim test trullas and skolnick 1990. To substantiate the hypothesis that any antidepressant like activity obtained with icariin resulted from the regulation of neurochemical and neuroendocrine systems the effects of oral 21 consecutive day treatment with icariin on brain mao activity was studied in the mouse fst model.

In fact horny goat weed is reported to act on sexual functions through three different pathways. Agmatine itself can act as an antagonist of nmda receptors which suggests its antidepressant like action. Icariin was found to significantly shorten immobility time in the forced swimming test fst after orally administration for 21 consecutive days.

Antidepressant like effect of icariin and its possible mechanism in mice pan ying. Sun j1 wang f2 hong g3 pang m4 xu h4 li h4 tian f4 fang r4 yao y4 liu j5. The behavioral neurochemical and neuroendocrine effects of icariin isolated from epimedium brevicornum were investigated in behavioral despair models of kunming strain of male mice.

In mice and its possible mechanism of action aarti khulbe savita pandey and sangeeta pilkhwal sah department of pharmaceutical sciences kumaun university nainital uttarakhand india. Jiang fuxin 2005 12 01 000000 the behavioral neurochemical and neuroendocrine effects of icariin isolated from epimedium brevicornum were investigated in behavioral despair models of kunming strain of male mice. Antidepressant like action of the hydromethanolic flower extract of tagetes erecta l.

The present study was undertaken to evaluate the antidepressant like effect of celastrus paniculatus seed oil in unstressed mice and to explore its mechanism of action. This effect on free calcium is achieved via an enzyme called phosphodiesterase type 5 pde5. Garlic extract 25 50 and 100 mgkg po administered to mice for 14 successive days decreased immobility periods significantly in a dose dependent manner as compared to control in both tst and fst indicating significant antidepressant like activity.

The first effect from icariin comes from its effect on the level of free calcium in the smooth muscles of the penis.

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